Nasolabial folds, commonly known as "smile lines" or "laugh lines," are the lines or creases that run from the sides of the nose to the corners of the mouth. These folds become more prominent with age and are a natural part of the aging process. While nasolabial folds are a common occurrence, their appearance can vary among individuals. Nasolabial folds are primarily formed due to a combination of factors. The loss of collagen and elastin in the skin, coupled with the effects of gravity, leads to a reduction in skin elasticity.Â